In the kitchens of the CAR-T, the modern immunotherapy in opposition to most cancers: “It is a revolution” | EUROtoday

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A healthcare worker manipulates the bioreactors where the CAR-T therapy is manufactured, in the immunology laboratory of the Hospital Clinic of Barcelona.

Within the partitions of the Hospital Clínic of Barcelona, ​​in a spherical journey by not more than three corridors and some stairs, an modern immunotherapy in opposition to most cancers is deliberate, manufactured and administered that has modified the prognosis of some blood tumors: it’s CAR-T remedy, a piece of genetic engineering that retrains the affected person’s immune system to raised struggle malignant cells. There are already a handful of medicines of this kind manufactured by the pharmaceutical trade, however the Clínic has been a pioneer within the improvement of an educational CAR-T with which they’ve already handled greater than 650 sufferers with out therapeutic alternate options. “We went from treating seven patients in 2017 to 114 in 2025. It is a revolution and I do not see a limit,” says hematologist Julio Delgado, head of the Oncoimmunotherapy Unit. “There are more and more indications, more clinical trials… And the beautiful thing is that, since we do it, we set the limit ourselves, we do not depend on the pharmaceutical industry to do it,” he emphasizes.

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The patients Juan Carlos del Val (left) and David Zafra (right), together with the hematologist Julio Delgado, in the corridors of the Clínic.Detail of the cell separator where blood components are separated to collect the T lymphocytes necessary for CAR-T therapy.
Patients in the Apheresis Unit of the Hospital Clínic of Barcelona. DVD 1307 Barcelona, ​​02/26/2026 CAR-T therapy report at the Hospital Clìnic. Photo: Gianluca BattistaThe technical director of the Clínic's Immunology laboratory, Daniel Benítez, opens one of the cryopreservation vats where CAR-T cells are preserved before being infused into patients.Patients David Zafra (from behind) and Juan Carlos del Val (center), along with hematologists Carlos Fernández de Larrea and Julio Delgado (from behind, on the right).
https://elpais.com/salud-y-bienestar/2026-04-28/en-las-cocinas-de-los-car-t-la-innovadora-inmunoterapia-contra-el-cancer-es-una-revolucion.html