The more and more affected non-smokers | EUROtoday

The more and more affected non-smokers
 | EUROtoday

” LOrsque we see people aged 30 or 35 with lung cancer, these are generally people who have never smoked, ”said the BBC Andreas Wicki, oncologist at the Zurich University Hospital. Between 10 and 20 % of cases of lung cancer worldwide concern people who have never smoked, according to the International Center for Research on Cancer (Circ). This proportion is increasing, in a context where tobacco consumption has been down for several years.

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The illness not impacts solely profiles historically related to lung most cancers: girls, particularly younger folks, are right now involved. In those that don’t smoke, probably the most incessantly noticed sort of tumor is adenocarcinoma, a kind that develops in pulmonary mucus. Cancer that evolves discreetly, thus delaying the prognosis. And within the majority of circumstances, the illness is due to this fact detected at a complicated stage.

Pollution, genetics, passive publicity

To clarify this explosion of lung cancers in non-smokers, a number of components have been discovered. Researchers designate, for instance, air air pollution, specifically high quality particles, as a figuring out issue. “Our study proposes that fine particles do not directly mutate DNA, but that they awaken dormant mutant cells in the lungs,” explains William Hill, researcher on the Francis Crick Institute in London.


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The kangaroo of the day

Answer



For some sufferers, these mutations are current from the beginning. This is especially the case of the EGFR gene, which was discovered incessantly in Asian girls with lung most cancers with out a smoking historical past. This gene has enabled the emergence of focused therapies, which enhance life expectancy. But specialists insist: screening continues to be too oriented in direction of people who smoke.

The historic concentrate on tobacco due to this fact results in neglecting sure indicators. And for researchers interviewed by the BBC, it’s completely essential to broaden the screening standards and assessment public insurance policies accordingly.


https://www.lepoint.fr/sante/cancer-du-poumon-les-non-fumeurs-de-plus-en-plus-touches-07-06-2025-2591488_40.php